It is believed that one in five or six couples has trouble getting pregnant. Statistics are ruthless.
Our centre offers a variety of infertility treatment methods, ranging from the most uncomplicated to the most sophisticated, for infertile couples. Depending on health disorders, a man, a woman or they both receive special-purpose medicines and undergo surgeries. Various insemination procedures help to solve more serious infertility problems.
Semen analysis (spermogram)
Semen analysis is performed in accordance with the requirements set by the World Health Organization (WHO). Semen analysis provides information about semen physical properties, semen motility, morphology and function tests.
Sperm genetic test for sperm maturity
Hyaluronan binding assay (HBA) – an analysis based on the sperm-hyaluronan-binding assay (HA).
The sperm-hyaluronan-binding assay is:
Hyaluronan binding assay plays an important role in the investigation of causes of male infertility. Only mature spermatozoa with developed receptors for hyaluronan acid can bind to the plate coated with the material. The binding reaction shows the proportion of mature spermotozoa in the sample (HBA %).
AB has been proven to be a valuable analysis which shows spermotozoa ability to fertilize the oocytes and helps to select sperm samples for the Physiological Intracytoplasmic Sperm Injection procedure (PICSI).
HBA helps to significantly reduce Pregnancy Loss Rates.
A combination of the diagnostic abilities of HBA and HA-sperm selection using the PICSI technique has proven to improve Clinical Pregnancy Rates. Pregnancy Loss Rate in patients diagnosed with low HBA scores (≤65% binding ratio) has significantly decreased.
A Postcoital Test (PCT)
is performed several hours after the intercourse. This test is used to examine the motility of spermatozoa in natural medium and female antigen antibody reaction. The test is performed in the cases of immunological infertility (immunologic incompatibility).
One-Stop Infertility Assessment
A one-stop approach offers a complete investigation necessary to determine the possible causes of infertility just in one day. This is a versatile evaluation of woman’s reproductive organs with the help of a transvaginal endoscopy. The procedure is performed under a local or intravenous anaesthesia allowing evaluation of the endometrial cavity and its possible abnormalities, pelvic organs, ovaries, fallopian tubes, and a review of the tubal patency. Based on the results obtained, we provide a precise diagnosis of disorders and whether they need to be treated. Male semen undergoes analysis at the same time in order to obtain as much information as possible for the couple.
Intrauterine insemination (IUI)
IUI is a type of infertility treatment in which partner’s semen is prepared and placed in the uterus using a fine catheter provided that one or both fallopian tubes are open. The procedure is performed during a natural or stimulated menstrual period.
Intrauterine Insemination (IUI) using special EVIE pump
A new method for intrauterine insemination (IUI) uses slow introduction techniques for the prepared sperm using an EVIE pump. The EVIE pump allows for slow (over 3-4 hours) injection of the prepared sperm into the uterus. Imitating the natural process, such a system of slow injection increases the possibility of fertilisation as a larger quantity of the motile sperm enters the uterus over a long period of time, increasing the possibility for the sperm to reach the oocyte.
Intrauterine Tuboperitoneal Insemination (IUTPI) (L. Mamas method)
IUTPI is a new insemination technique involving the usage of 10 ml of specifically prepared sperm. Clinical experience has shown that four millimetres of inseminate carrying spermatozoa were not sufficient for fallopian tube sperm perfusion.
In this case, a bigger volume of prepared sperm is used, thus increasing the intrauterine pressure during the procedure.
In vitro fertilisation (IVF)
IVF is an artificial method of fertilisation in vitro involving stimulation of ovaries, paracentesis of ovaries and oocyte aspiration into test tubes. The retrieved woman’s oocytes undergo fertilisation in the laboratory culture dish by means of a suspension of sperm collected from her partner. Fertilised oocytes remain for growing for two or three days (or in accordance with necessity, patients’ preferences – up to blastocyst stage, five or six days after fertilisation), and after that, embryos or a blastocyst are placed in the woman’s uterine cavity.
ERA analysis (Endometrial Receptivity Analysis) is particularly topical for those couples who do not succeed in natural conceiving with the help of the IVF (in vitro fertilisation procedure) that involves a transfer of an embryo of good quality into the uterus. This analysis helps to determine when the endometrium is most receptive for an embryo transfer and implantation. An obstetrician gynaecologist assigns and conducts this analysis.
Intracytoplasmic Sperm Injection (ICSI)
ICSI is a technique in which a single sperm is injected into an oocyte after stimulation of the ovaries, paracentesis of ovaries and oocyte aspiration into test tubes. The Oocytes undergo fertilisation by means of a micromanipulator. A sperm cell selected from her partner is injected directly into the centre of the egg. Fertilised oocytes remain for growing for two or three days (or in accordance with necessity, patients’ preferences – up to blastocyst stage, five or six days after fertilisation), and after that, embryos or a blastocyst are placed in the woman’s uterine cavity.
Application of physiologically selected sperm to ICSI. Spermatozoa selected using this technique are more mature and have fewer chromosomal aneuploidies.
This is a process of growing an embryo for five or six days by which time it reaches a higher stage of physiological development. Growing an embryo in a laboratory to the blastocyst stage allows selecting the best embryos to transfer to the uterus.
Embryo growth in low oxygen concentration
The state-of-the-art three gas mixture is used for embryo growth at Northway Fertility Centre. How does it influence the outcome of fertilisation? Scientists working the field of Reproductive Medicine are constantly looking for new ways to make the best use of infertility treatment techniques, the In Vitro Fertilisation and Intracytoplasmic Sperm Injection (ICSI). Many studies focused on the improvement of the medium where human embryo grows before its implantation into the uterus. Research suggests that oxygen concentration is a crucial factor to successful embryo growth. Embryos traditionally cultured in oxygen concentration that corresponds to the one in the air (~20%). However, natural environment where an embryo is being cultured contains a lesser concentration of oxygen (from 2% to 8%). The analysis of the scientific data revealed that embryonic development by using the determined concentration of oxygen can improve such success outcome after the IVF and ICSI as the Clinical Pregnancy Rate and a number of births.
EmbryoScope Time-Lapse for Embryo Monitoring
The Time-lapse system (non-invasive periodical imaging) offers an interruptible monitoring of embryo development and selection of the best suitable embryos of high quality for the transfer into the uterus. According to specialists, this incubator undoubtedly increases the success rate of fertilisation procedures. Sometimes embryos divide into three cells at once, thus bypassing the second stage. This embryo is absolutely not suitable for an implantation. A thorough analysis of the data obtained helps to select an embryo with optimum implantation capabilities.
Vitrification (freezing and storage)
Freezing of oocytes, zygotes, embryos and blastocyst is an extremely fast process of freezing the germ cells retrieved from a woman and storing them in liquid nitrogen till patients decide to thaw them. Transfer of thawed embryos allows negating the need for recurring assisted reproductive procedures and application of medications for ovarian stimulation. In this way, woman’s health is being spared.
Sperm freezing provides an opportunity to have your own children in the future in case of chemotherapy, roentgenotherapeutic or surgical treatment of oncological diseases occur that would otherwise keep you from having children. Later when the male recovers, his thawed sperm can be used for fertilisation of his partner with the help of the assisted reproductive procedures like IUI, IVF or ICSI.
Sperm aspiration from ovaries (TESA)
TESA is a microsurgical procedure that involves taking the vesicle vessels from the testicles to examine for sperm content. TESA can serve as a diagnostic tool when the semen analysis reports no spermatozoon content. Spermatozoon retrieved during TESA can also be used during the ICSI procedure.